American Heritage® Dictionary of the English Language, Fourth Edition
- adj. Activated by or capable of liberating acetylcholine, especially in the parasympathetic nervous system.
- adj. Having physiological effects similar to those of acetylcholine: a cholinergic agent or drug.
- adj. biochemistry Of, pertaining to, activated by, producing or having the same function as acetylcholine
- adj. releasing or activated by acetylcholine or a related compound
- choline + -ergic (Wiktionary)
- (acetyl)cholin(e) + -ergic. (American Heritage® Dictionary of the English Language, Fourth Edition)
“And during the first few minutes you might have some symptoms which we call cholinergic symptoms, which are sweating, salivating, lacrimating, maybe some shortness of breath.”
“Too much, and they become paralyzed -- that's called a cholinergic crisis.”
“As a result, those nerve fibers which secrete acetylcholine are referred to as cholinergic nerves and those which secrete norepinephrine are adrenergic nerves.”
“The drugs in question are known as cholinergic agents, which interact with the brain to counter nicotine addiction.”
“In view of such exceptions, it seemed to me desirable to have a terminology enabling us to refer to a nerve fibre in terms of the chemical transmission of its effects, without reference to its anatomical origin; and, on this functional basis, I11 proposed to refer to nerve fibres and their impulses as "cholinergic" or "adrenergic", as the case might be.”
“The most common cause of such excessive sweating is overactivity of the nerves in the autonomic nervous system which control a host of glandular secretions – technically, the cholinergic nerves.”
“In addition, advanced age is associated with increased susceptibility to anti-cholinergic drugs because of a reduction in acetylcholine activity with age.”
“Anti-cholinergic Herbs: Numerous herbs and natural products have anti-cholinergic effects and may be more hazardous than medications.”
“These drugs were shown to have anti-cholinergic effects at high concentration.”
“Note: Fexofenadine (Allegra) and cetirizine (Zyrtec) are antihistamines without anti-cholinergic effects, but may cause sedation.”
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Takes 12-15 years and $800 million to bring a drug to the market. For every 10,000 compounds that go through animal studies, 10 will go to human trials (3 phases) to get 1 to the market.
A roster of adjectives that infrequently surface in typical conversation and writing. Many are dredged from scientific or other technical jargon or sieved from examples of disused archaic forms.
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