interleukin

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ACVS, an assistant professor of equine orthopedic research at Colorado State University in Fort Collins, Colo., has performed a number of in vitro studies in which chunks of equine cartilage are grown in a culture medium and manipulated to simulate arthritic changes found in intact joints by the addition of destructive proteins (such as interleukin-1).

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Definitions (1)

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  1. any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system

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Examples (50)

  • RoACTEMRA is the first interleukin-6 (IL-6) receptor-inhibiting monoclonal antibody developed for the treatment of RA and is a novel approach to help tackle this debilitating disease. —  WebWire | Recent Headlines
  • There are several key cytokines, or proteins, involved in the inflammatory process including tumor necrosis factor (TNF) alpha, interleukin-1 (IL-1) and interleukin-6 (IL-6). —  WebWire | Recent Headlines
  • It is an anti-interleukin-6 receptor antibody, which has a different mechanism of action than the anti-tumor necrosis factor therapies on the market now. —  FierceBiotech
  • These depend on the presence of the growth factor interleukin-3 by combining them in microtissues with CHO cells (Chinese hamster ovary cells) that were engineered to secrete interleukin-3. —  DailyTech Main News Feed
  • Stelara (ustekinumab), the first in a new class of biologics which targets the cytokines interleukin-12 and -23, has been approved by the European Commission specifically for the treatment of moderate to severe plaque psoriasis in adults who failed to respond to other systemic therapies including ciclosporin, methotrexate and PUVA (psoralen plus ultraviolet A light). —  PharmaTimes World News
 

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