from The American Heritage® Dictionary of the English Language, 4th Edition
- adj. Having valence 4.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- adj. having a valence of 4
from the GNU version of the Collaborative International Dictionary of English
- adj. Having a valence of four; tetratomic; quadrivalent.
from The Century Dictionary and Cyclopedia
- Same as quadrivalent.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- adj. haveing a valence of four
Sorry, no etymologies found.
Since there are four distinct dengue viruses, the challenge is to concoct a four-way, or "tetravalent," vaccine, effective against all strains at once.
The new vaccine is tetravalent, meaning that it is designed to protect against all four dengue viruses, also called serotypes.
Every node in this graph was tetravalent: connected by four edges to four other nodes.
SnCl_ ; the stannic, in which it is tetravalent as shown in the compounds SnO_ , SnS_ .
Finally one atom of a tetravalent element such as carbon will combine with four atoms of a univalent element, as in the compound
As part of that electron transfer reaction, hexavalent uranium (which has a charge of +6) becomes tetravalent uranium (which has a charge of +4).
In 2010, the first TandAb antibody AFM13 entered clinical trials and the bispecific, tetravalent human antibody has shown very promising safety, tolerability and activity in the treatment of Hodgkin Lymphoma.
Affimed's proprietary and highly productive TandAb® technology enables the company to generate unique tetravalent, bispecific, fully human antibody formats that promise increased therapeutic potential and superior profiles compared to monoclonal antibodies.
TandAbs®, which were invented and developed by Affimed scientists, are tetravalent bispecific antibody formats that have two binding sites for each antigen.
"Our overall strategy was to identify the best individual candidate for each serotype, based on safety and ability to induce an immune response, and to then combine those into a tetravalent vaccine," explains Dr. Whitehead.
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