from Wiktionary, Creative Commons Attribution/Share-Alike License
- adj. That causes vasoconstriction
from The Century Dictionary and Cyclopedia
- Same as vasoconstrictor.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. any agent that causes a narrowing of an opening of a blood vessel: cold or stress or nicotine or epinephrine or norepinephrine or angiotensin or vasopressin or certain drugs; maintains or increases blood pressure
Sorry, no etymologies found.
Your article failed to mention that GSK's concern related to an unsubstantiated theory being advanced by Dr. Mary Money that these adverse events were due to a direct vasoconstrictive effect on the pulmonary circulation, which could lead to a condition known as primary pulmonary hypertension.
Due to concerns about potential adverse vasoconstrictive effects on regional vascular beds, such as the liver and the kidney, norepinephrine traditionally had either not been used or had been reserved as a last resort in a moribund patient, with predictably poor results.
Thus, large doses of the drug may be required in some patients with septic shock, possibly due to α-receptor down-regulation in sepsis. 111 Cardiovascular Effects Norepinephrine therapy usually causes a clinically significant increase in MAP attributable to its vasoconstrictive effects, with little change in HR or cardiac output, leading to increased systemic vascular resistance.
Case mothers were more than four times as likely as control-group mothers to report use of at least one vasoconstrictive recreational drug before pregnancy.
When her blood pressure and pupillary response were normal, the next things we looked at were room humidity, air filtration, and aromatherapy, if you will, with eucalyptus oil, often safer and more effective than vasoconstrictive decongestants.
Wordnik is becoming a not-for-profit! Read our announcement here.