Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A platinum-containing chemotherapeutic drug, Cl2H6N2Pt, used in the treatment of metastatic ovarian or testicular cancers and advanced bladder cancer.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A simple organic compound of platinum, cis-diamminedichloroplatinum(II), that is used as a chemotherapy agent against several types of cancer.

Etymologies

cis- + platin(um).
(American Heritage® Dictionary of the English Language, Fourth Edition)

Examples

  • Another chemotherapy drug, cisplatin, which is essential in the treatment of testicular cancer, is also in short supply.

    Cancer drug shortages getting worse, FDA says

  • Einhorn suggested a last-ditch effort: a new chemical called cisplatin.

    The Emperor of All Maladies

  • In particular, a commonly used cancer drug called cisplatin often causes nausea, vomiting and appetite loss -- and cuts the body's natural ghrelin levels.

    Reuters: Press Release

  • The India-US research team has worked on a chemotherapeutic drug called cisplatin, the first choice of treatment against a range of malignancies, including cancers of the breast, cervix, lungs and ovaries.

    The Telegraph - Calcutta (Kolkata) - Frontpage

  • The new research, supported by the Medical Research Council (MRC), studied the use of a drug called cisplatin, a platinum-based molecule which directly affects the DNA strands within cells to cause controlled cell death or 'apoptosis'.

    PhysOrg.com - latest science and technology news stories

  • In mice with melanoma, a cancer typically found in skin, this method slowed the growth of the tumors and increased the effectiveness of the chemotherapy drug they were given, cisplatin, which is used to treat most cancers.

    PhysOrg.com - latest science and technology news stories

  • Platinum-based compounds, such as cisplatin and oxaliplatin, are the cornerstone in the treatment of testicular, ovarian, colorectal, lung and other cancers but their effectiveness is limited by the relatively low therapeutic ratio, the ratio of the maximally tolerated dose of the drug to the effective dose, and the frequent occurrence of drug resistance leading to cancer recurrence.

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  • Michael Link , the president-elect of the American Society of Clinical Oncology, said the drug cisplatin is in short supply and is a mainstay treatment of testicular cancer.

    Drug Shortages Distress Hospitals

  • Einhorn wanted to combine cisplatin with two other drugs to see if he could increase the response rate.

    The Emperor of All Maladies

  • In 1976, the year that the NSABP-04 trial struggled to its midpoint, a novel drug, cisplatin, appeared in the cancer wards.

    The Emperor of All Maladies

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