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Zhang Z, Tong T (2001) Characterization of regulatory elements on the promoter region of p16 (INK4a) that contribute to overexpression of p16 in senescent fibroblasts.— PLoS ONE Alerts: New Articles
Rates of spontaneous translocation assessed during the serial growth of wild type and His+ recombinants recovered from ten independent wild type and senescent est2Δ / est2Δ cultures that carried the his3-Δ3′ substrate at either the— PLoS ONE Alerts: New Articles
This indicates that spontaneous translocation formation occurs by the same conservative mechanism in wild type and senescent est2Δ / est2Δ homozygotes, regardless of the locations of the substrates.— PLoS ONE Alerts: New Articles
Surprisingly, we found that with the his3-Δ3′ substrate at the CAN1 locus, the frequency of DSB-stimulated translocation in est2Δ / est2Δ homozygotes was reduced 12 - to 20-fold, regardless of whether the cells were from pre-senescent, senescent or post-senescent cultures.— PLoS ONE Alerts: New Articles
Upon examining DSB-stimulated translocation in cells where the his3-Δ3′ substrate was at the HIS3 locus, we found that the est2Δ allele had a similar effect, as the frequency was reduced 14 - to 60-fold in the est2Δ / est2Δ homozygote regardless of whether the cells were pre-senescent, senescent or post-senescent.— PLoS ONE Alerts: New Articles

American Heritage Dictionary (1)
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