senescence

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Cellular senescence is a process leading to terminal growth arrest with characteristic morphological features.

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Definitions (4)

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  1. The condition of growing old, or of decaying by time; decadence. The world with an unearthly ruddy Hue; such might be the color cast by a nearly burnt-out sun in the senescence of a system. Harper's Mag., LXXVII. 620.

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Examples (43)

  • A new consensus of gerontologists proposes that delay of biological senescence is the most potent public health measure for preventing chronic disease in late life. —  Fight Aging!
  • The most likely candidates for delaying senescence are the longevity-linked heat shock protein axis regulated by HSF1. —  Fight Aging!
  • Cellular senescence is also a phenotype induced by p53 activation and plays a critical role in protecting against tumor development. —  CiteULike: Everyone's library
  • Cellular senescence is a process whereby a cancer cell essentially "goes to sleep."
  • Chemical compounds against these targets that will drive prostate cancer cells into a state of senescence will be evaluated in specialized animal models of prostate cancer with the goal of clinical translation.
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Roget's II Roget's II: The New Thesaurus

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Roget's II: The New Thesaurus, Third Edition by the Editors of the American Heritage® Dictionary. Copyright © 2003, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
 

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