cirrhosis

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Replicative senescence that occurs in hepatocytes in culture and in liver cirrhosis is associated with lack of telomerase activity and results in telomere shortening.

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Definitions (11)

Toggle American Heritage definitions American Heritage Dictionary (2)

  1. noun A chronic disease of the liver characterized by the replacement of normal tissue with fibrous tissue and the loss of functional liver cells. It can result from alcohol abuse, nutritional deprivation, or infection especially by the hepatitis virus.
  2. noun Chronic interstitial inflammation of any tissue or organ.

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Toggle GNU Webster definitions GNU Webster's 1913 (1)

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Examples (38)

  • When I was a kid my grandad was in the hospital with cirrhosis, and they made me go see him every week. —  EBSCOhost
  • With alcoholic cirrhosis, the normal cells of the liver die, and are replaced with scar tissue. —  BellaOnline - The Voice of Women
  • Taking Tylenol can be safe if you take less than six tablets a day and ibuprofen can be safe to if you have no ulcers, cirrhosis, and have normal kidneys. —  Find Free Articles - ArticlesBase
  • Having cirrhosis, a high protein diet is recommended, though red meat should be avoided. —  Find Free Articles - ArticlesBase
  • Liver transplantation is widely accepted as a standard method of treatment for many patients with advanced cirrhosis, and survival rates among patients who have undergone liver transplantation approach 80\% at 3 years. 1 These success rates, together with —  New England Journal of Medicine
 

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Etymologies (2)

Toggle American Heritage etymologies American Heritage Dictionary (1)

  1. New Latin : Greek kirros, tawny (from the color of the diseased liver) + -osis.

Toggle Century etymologies Century Dictionary (1)

  1. New Latin (later F. cirrhose), from Greek κίρρος, tawny, + -osis.
 

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/sɪˈroʊsɪs/
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