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Definitions

American Heritage® Dictionary of the English Language, Fourth Edition

  1. n. A thickening or hardening of a body part, as of an artery, especially from excessive formation of fibrous interstitial tissue.
  2. n. A disease characterized by this thickening or hardening.
  3. n. Botany The hardening of cells by the formation of a secondary wall and the deposition of lignin.

Century Dictionary and Cyclopedia

  1. n. A hardening or induration; specifically, the increase of the sustentacular tissue (neuroglia, or connective tissue) of a part at the expense of the more active tissue.
  2. n. In botany, the induration of a tissue or cell-wall either by thickening of the membranes or by their lignification (that is, by the formation of lignin in them).

Wiktionary

  1. n. pathology The abnormal hardening of body tissues, such as an artery.

GNU Webster's 1913

  1. n. (Med.) Induration; hardening; especially, that form of induration produced in an organ by increase of its interstitial connective tissue.
  2. n. (Bot.) Hardening of the cell wall by lignification.

WordNet 3.0

  1. n. any pathological hardening or thickening of tissue

Etymologies

  1. From Ancient Greek σκλήρωσις (sklerosis, "an induration"), from *σκληροῦν (skleroyn, "to harden, indurate"), from σκληρός (skleros, "hard") (Wiktionary)
  2. Middle English sclirosis, from Medieval Latin sclīrōsis, from Greek sklērōsis, hardening, from sklēroun, to harden; see scleroma. (American Heritage® Dictionary of the English Language, Fourth Edition)

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‘sclerosis’ has been looked up 1694 times, loved by 1 person, added to 10 lists, and has a Scrabble score of 11.