stroma

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A few years ago, Dr. Funderburgh and other University of Pittsburgh researchers identified stem cells in a layer of the cornea called the stroma, and they recently showed that even after many rounds of expansion in the lab, these cells continued to produce the biochemical components, or matrix, of the cornea.

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Definitions (14)

Toggle American Heritage definitions American Heritage Dictionary (2)

  1. noun The connective tissue framework of an organ, gland, or other structure, as distinguished from the tissues performing the special function of the organ or part.
  2. noun The spongy, colorless framework of a red blood cell or other cell.

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Examples (50)

  • Because other studies have suggested that gene expression patterns in the nearby tissue, or stroma, are altered in tumors that are prone to metastasis, the investigators conducted transplant experiments by putting highly metastatic tumor cells into the mammary fat pads of mice that have either a high or a low susceptibility to tumor metastasis. —  RxPG News : Latest Medical, Healthcare and Research News
  • In an article, 'A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer 'i, published in Nature Medicine, Dr Pierre Farmer and colleagues showed the potential of the reactive stroma to modulate tumor phenotype and the clinical response to treatment. —  PhysOrg.com - latest science and technology news stories
  • In an article, 'A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer 'i, published in —  EurekAlert! - Breaking News
  • A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer. —  EurekAlert! - Breaking News
  • Laser capture microdissection-coupled real-time RT-PCR and immunohistochemistry further demonstrated that cell proliferation in the stroma, but not the epithelium, is significantly reduced in PCOSE. —  The Journal of Clinical Endocrinology & Metabolism Current Issue
 

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Etymologies (2)

Toggle American Heritage etymologies American Heritage Dictionary (1)

  1. Late Latin strōma, mattress, covering, from Greek, bed; see ster-2 in Indo-European roots.

Toggle Century etymologies Century Dictionary (1)

  1. New Latin, from Latin stroma, from Greek στρω̄μα (στρωματ-), a covering, a coverlet, from στρωννύναι, στορεννύναι, spread, spread out, strew: see strew, stratum.
 

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/ˈstroʊmə/
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