from The American Heritage® Dictionary of the English Language, 4th Edition
- adj. Edged with toothlike projections; toothed: dentate leaves.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- adj. Having teeth or toothlike projections; serrated, toothed.
from the GNU version of the Collaborative International Dictionary of English
- adj. Toothed; especially, with the teeth projecting straight out, not pointed either forward or backward.
- adj. Having teeth or toothlike points. See Illust. of Antennæ.
from The Century Dictionary and Cyclopedia
- Toothed; notched.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- adj. having toothlike projections in the margin
Under the microscope, it appeared that the transplanted cells had settled mainly in a sub-area of the hippocampus called the dentate gyrus.
The hippocampus plays a central role in the creation and storage of new memories, and central to that function is the creation of neurons from "neural precursor cells" - stem cells-within the part of the hippocampus called the dentate gyrus.
The researchers built on earlier studies that found that the production of stem cells in the area of the hippocampus known as the dentate gyrus drops off dramatically by the time mice are middle age and that exercise can slow that trend.
It rouses the nerve cells in a part of the brainstem called the dentate gyrus into a frenzy.
Exercise, the researchers found, targets a region of the brain within the hippocampus, known as the dentate gyrus, which underlies normal age-related memory decline that begins around age 30 for most adults.
Exercise strengthens a section of the hippocampus, called the dentate gyrus, which helps to build new neurons, strengthen and build myelin and increase brain volume - even in old age.
Previously, using high-resolution brain imaging, Dr. Small and his colleagues discovered that decreasing brain function in one area of the hippocampus, called the dentate gyrus, is a main contributor of normal decline in memory as we age.
In a paper, published in Neuron, Dr. John Roder, Senior Investigator at the Lunenfeld, and Bechara Saab, Ph. D candidate at the Lunenfeld, studied the interaction of two proteins in a small region of the brain called the dentate gyrus (part of the hippocampus, which plays a role in long-term memory and spatial navigation).
"In humans, monkeys and rats," he says, "normal aging targets a node called the dentate gyrus, while a different node--the entorhinal cortex--is relatively spared.
Finally, they measured the level of stress hormones in their blood -- specifically, the hormones known as "glucocorticoids" -- and then "decapitated" (to use scientific parlance) the critters to see if new cells had sprouted in the dentate gyrus of their brains.
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