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Definitions

American Heritage® Dictionary of the English Language, Fourth Edition

  1. v. To make poisonous or noxious.
  2. v. To embitter.

Century Dictionary and Cyclopedia

  1. To taint or impregnate, as meat, drink, or weapons, with venom or any substance noxious to life; make poisonous: chiefly in the past participle: as, an envenomed arrow or shaft; an envenomed potion.
  2. Figuratively, to imbue as it were with venom; taint with bitterness or malice.
  3. To make odious or hateful.
  4. To make angry; enrage; exasperate.

Wiktionary

  1. v. To make poisonous
  2. v. To acerbate

GNU Webster's 1913

  1. v. To taint or impregnate with venom, or any substance noxious to life; to poison; to render dangerous or deadly by poison, as food, drink, a weapon; ; also, to poison (a person) by impregnating with venom.
  2. v. To taint or impregnate with bitterness, malice, or hatred; to imbue as with venom; to imbitter.

WordNet 3.0

  1. v. add poison to
  2. v. cause to be bitter or resentful

Etymologies

  1. Middle English envenimen, to poison, from Old French envenimer : en-, cover with; see en-1 + venim, venom; see venom.

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‘envenom’ has been looked up 1466 times, added to 4 lists, and has a Scrabble score of 12.