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Definitions

American Heritage® Dictionary of the English Language, Fourth Edition

  1. v. To make hostile, unsympathetic, or indifferent; alienate.
  2. v. To remove from an accustomed place or set of associations.

Century Dictionary and Cyclopedia

  1. Foreign; strange.
  2. Reserved; haughty.
  3. n. A stranger; a foreigner.
  4. To alienate; divert from its original use or possessor; apply to a purpose foreign to its original, proposed, or customary one.
  5. To alienate the affections of; turn from kindness to indifference or enmity; turn from intimate association to strangeness, indifference, or hostility.
  6. To keep at a distance; withdraw; withhold: generally used reflexively.
  7. To cause to appear strange or foreign.

Wiktionary

  1. v. To cause to feel less close or friendly; alienate. To cease contact with (particularly of a family member or spouse, especially in form term).
  2. v. To remove from an accustomed place or set of associations.
  3. n. foreign; oversea
  4. n. foreign; oversea
  5. adj. strange; odd; bizarre

GNU Webster's 1913

  1. v. To withdraw; to withhold; hence, reflexively, to keep at a distance; to cease to be familiar and friendly with.
  2. v. To divert from its original use or purpose, or from its former possessor; to alienate.
  3. v. To alienate the affections or confidence of; to turn from attachment to enmity or indifference.

WordNet 3.0

  1. v. arouse hostility or indifference in where there had formerly been love, affection, or friendliness
  2. v. remove from customary environment or associations

Etymologies

  1. Middle English estraungen, from Old French estrangier, from Latin extrāneāre, to treat as a stranger, disown, from extrāneus, foreign; see strange.

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‘estrange’ has been looked up 1593 times, loved by 3 people, added to 12 lists, and has a Scrabble score of 9.