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Definitions

American Heritage® Dictionary of the English Language, Fourth Edition

  1. v. To incur the dislike of; provoke hostility or enmity in: antagonized her officemates with her rude behavior.
  2. v. To counteract.

Century Dictionary and Cyclopedia

  1. To act in opposition to; oppose; counteract; hinder.
  2. To act antagonistically or in opposition.
  3. Also spelled antagonise.

Wiktionary

  1. v. To work against; oppose; especially to incite reaction.

GNU Webster's 1913

  1. v. To contend with; to oppose actively; to counteract.
  2. v. To act in opposition.

WordNet 3.0

  1. v. provoke the hostility of
  2. v. act in opposition to

Etymologies

  1. Greek antagōnizesthai, to struggle against : anti-, anti- + agōnizesthai, to struggle (from agōn, contest; see agony).

Examples

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‘antagonize’ has been looked up 1478 times, loved by 2 people, added to 35 lists, and has a Scrabble score of 20.