Definitions
American Heritage® Dictionary of the English Language, Fourth Edition
- n. Any of a class of enzymes that catalyze the linkage of two molecules, generally utilizing ATP as the energy donor. Also called synthetase.
Wiktionary
- n. biochemistry Any of a group of enzymes that catalyze the binding of two molecules; synthetase.
GNU Webster's 1913
- n. (Biochem.) An enzyme which catalyzes creation of a covalent bond between two substrates, resulting in a larger product which is a combination of the two starting materials; especially, DNA ligase, an enzyme which creates a phosphate bond between 5′ and 3′ ends of a DNA chain, resulting in a longer chain of DNA. DNA ligase is important in normal biosynthesis of DNA in the replication cycle of cells.
Etymologies
- From Latin lig(are) ("to bind") + -ase. (Wiktionary)
- Latin ligāre, to bind; see leig- in Indo-European roots + -ase. (American Heritage® Dictionary of the English Language, Fourth Edition)
Examples
“S., and Ciechanover, A. (1983) "Components of ubiquitin-protein ligase system".”
“DNA is cut-up but don't be afraid/Yo Jackteria has an enzyme called ligase/An enzyme that will definitely”
WN.com - Articles related to Plants give up some deep secrets of drought resistance
“Jackteria has an enzyme called ligase/An enzyme that will definitely”
WN.com - Articles related to Plants give up some deep secrets of drought resistance
“Jackteria has an enzyme called ligase/An enzyme that will definitely why take enzymes and wheat grass juices why take enzymes it helps fights cancer and other dieases the hope group with cantron tells you to take pancrean and bromelie. bromelie is found in natural form in NONI JUICE anti inflamintory www. tni.com #1850064 for your noni! my brother could not eat for 3 weeks, he had stage 4 pancreatic cancer, until he started the noni cancer program that starts drinking one bottle a day for 4 days, 1/2 bottle a day for 10 days then”
WN.com - Articles related to Plants give up some deep secrets of drought resistance
“DNA polymerase, Pol I, extends the DNA from the free 3'-OH using its exonuclease activity to replace the nucleotide of the damaged base, as well as a few downstream, followed by sealing of the new DNA strand by DNA ligase.”
“Prediction and evolution of E3 ubiquitin ligase targets”
“One of them is an RNA ligase with weak polymerase activity.”
“Beta lactamases have kept these activities, despite structural changes which have resulted in losing DD-peptidyl ligase activity, if these activities are kept, then the enzyme is more robust than Axe contends but to be fair this is harder to monitor in the kinds of experiments Axe did.. gutbag”
Axe (2004) and the evolution of enzyme function - The Panda's Thumb
“At this point, however, unknowingly and unintentionally, we were extremely lucky when we used as model substrates commercial proteins such as BSA, lysozyme and RNase, that were all recognized (as we learnt later) by this ligase and via a similar targeting motif - their N-terminal residue.”
“Interestingly, the ligase involved in BSA ubiquitination is E3a that was discovered during my graduate studies.”
Lists
These user-created lists contain the word ‘ligase’.
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connexion
link, joining, junction, concatenation, hookup, isthmus, ligament, articulation, node, tie, relation, intersection and 86 more...
Tweets
Looking for tweets for ligase.
ruzuzu Has anyone made a list of common catalysts? Anyone? Anyone?
*would not be surprised either way*
*begins plotting out cat o' list pun (or equivalent)* Oct 24, 2010
fbharjo I used the more archaic noun form to see if it would catalyze any action. Voilà! Oct 24, 2010
Prolagus I think you mean a catalyst. Oct 24, 2010
fbharjo a catalysis in linking DNA Oct 23, 2010