American Heritage® Dictionary of the English Language, Fourth Edition
- n. A factor that renders the administration of a drug or the carrying out of a medical procedure inadvisable: A previous allergic reaction to penicillin is a contraindication to the future use of that drug.
Century Dictionary and Cyclopedia
- n. In medicine, an indication from some peculiar symptom or fact that forbids the method of cure which the main symptoms or nature of the disease would otherwise call for. Also counter-indication.
GNU Webster's 1913
- n. (med.) An indication or symptom which forbids the method of treatment usual in such cases.
- n. (medicine) a reason that makes it inadvisable to prescribe a particular drug or employ a particular procedure or treatment
“F. CONTRAINDICATIONS: A contraindication is a specific situation in which a drug, procedure, or surgery should NOT be used, because it may be harmful to the patient.”
“A "contraindication" is a "situation  in which the drug should not be used because the risk of use ... clearly outweighs any possible therapeutic benefit.”
“The resubmission follows an agreement reached with an FDA committee seeking approval with a contraindication for women of childbearing potential.”
“Diego has shaved his head into a kind of flat Mohawk and, in contraindication of the rule against facial hair, has grown a soul patch; he looks like a Hare Krishna hipster.”
“It's a rare occurrence that there's a true egg allergy, but it does occur, and that is pretty much the one contraindication to flu vaccination.”
“Studies suggest that 5%-15% of those who ask for cosmetic surgery will be suffering from BDD – or body dysmorphic disorder – which some doctors consider an actual contraindication for surgical treatment, since sufferers may simply go on to develop different bodily preoccupations.”
“The release notes that while the sibutramine drug label already includes warnings against the use of sibutramine in patients with cardiovascular disease, based on the serious nature of the review findings, the FDA requested and the manufacturer agreed to add a new contraindication to the sibutramine drug label.”
“The general notion is that patients with significant BED should undergo cognitive behavioural intervention prior to surgery and that severe BED may be a contraindication to proceeding with any form of weight-loss.”
“The contraindication will state that sibutramine is not to be used in patients with a history of cardiovascular disease, including:”
“Thus, BED should not generally be seen as a contraindication to proceeding with gastric bypass surgery.”
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against or opposite; below or beyond
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