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  1. O love

Definitions

American Heritage® Dictionary of the English Language, Fourth Edition

  1. interj. Used before the name of or a pronoun referring to a person or thing being formally addressed: "How can I put it to you, O you who prepare to travel with important matters on your mind?” ( Jo Durden-Smith).
  2. interj. Used to express surprise or strong emotion: "O how I laugh when I think of my vague indefinite riches” ( Henry David Thoreau).
  3. The symbol for the element oxygen.
  4. abbr. Baseball out
  5. abbr. outstanding.

Wiktionary

  1. n. The fifteenth letter of the basic modern Latin alphabet.
  2. n. chemistry Symbol for oxygen.
  3. n. mathematics The upper bound function also known as big O.
  4. prep. grammar The English vocative particle (always in upper case), used for direct address in translations from languages which have the vocative case.
  5. interj. Expression of earnestness or reverence, used before the name of a deity or revered person in impassioned speech.
  6. n. The fifteenth letter of the English alphabet, called o and written in the Latin script.
  7. abbr. cricket The number of overs bowled
  8. n. A blood type that lacks A or B antigens and may only receive transfusions of similar type O blood, but may donate to all (neglecting Rh factor). Synonym: universal donor.
  9. n. printing American Library Association Abbreviation of octavo, a book size (20-25 cm).
  10. n. soccer Someone associated with Leyton Orient Football Club, as a player, coach, supporter etc.
  11. n. The ordinal number fifteenth, derived from this letter of the English alphabet, called o and written in the Latin script.

Etymologies

  1. Old Saxon gloss o (950s) in Lambeth ms. (957) of Gallican Psalter and ó, o (>1000) in Durham Hymns, regularly as redundant "o eala þu" and "ó eala þu" at uppercase proper names in paraphrase and some verbs in periphrase; Anglo-Norman O (~1200) in mss. of Sts. Juliana and Katherine, and other religiose writs; and English O, o (~1525) in The New Testament Translation by William Tyndale for Ancient Greek , Latin o (vocative, intensive: Old English èalà, æàlà, ǽlà, hèlà; also Middle English O (Actus 13:10; Romayns 9:20; Galaþies 3:1), ò (Romayns 2:1,3), Irish a (Maþeu 15:28;17:17; Luk 9:41;24:25; Actus 13:10) or A (Actus 27:21; Romayns 11:33)—sometimes mistranscribed as O in online bibles—, þou (1Tymoþe 6:20), ȝe (Actus 18:14), or (Actus 1:1; Ebrews 10:7) in Newe Testament by Iohn Wiclif (1382). intensive, interrogative: Old English ; English lo, oh (1534)) (Wiktionary)

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‘O’ has been looked up 1208 times, added to 7 lists, commented on 1 time, and is not a valid Scrabble word. It's also a palindrome.