demented

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Alzheimer’s Disease starts when a protein that should be folded up properly misfolds into a kind of demented origami.

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Definitions (5)

Toggle American Heritage definitions American Heritage Dictionary (2)

  1. adjective Mentally ill; insane.
  2. adjective Suffering from dementia or a loss of cognitive function.

Toggle Century definitions Century Dictionary (1)

Toggle GNU Webster definitions GNU Webster's 1913 (1)

Toggle WordNet definitions WordNet (1)

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Examples (50)

  • Alzheimer’s Disease starts when a protein that should be folded up properly misfolds into a kind of demented origami. —  Gregory Petsko on the coming neurological epidemic
  • He seemed almost demented, and hardly spoke a word. —  THE ISLAND OF SHEEP
  • Sometimes when I called she would sound very ... well, I guess demented is the correct term. —  AHMM, April 2002
  • I told her she was demented, and she began to cry, and said it was vital and more than her life was worth and God knows what else. —  Coroner's Pidgin - Margery Allingham - Campion 12: 1945
  • And from there came a landmark appearance in Ricky Gervais's Extras in 2005 in which he appeared as what can only be described as a demented parody of himself.
 

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Roget's II Roget's II: The New Thesaurus

Allen's Allen's Synonyms and Antonyms

Used in the same context Used in the Same Context

deranged ·  insane ·  crazed ·  delirious ·  psychotic ·  sadistic ·  frantic ·  maniacal ·  distraught ·  suicidal ·  intoxicated ·  hysterical
Roget's II: The New Thesaurus, Third Edition by the Editors of the American Heritage® Dictionary. Copyright © 2003, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
 

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/dəˈmɛntɛd/
by American Heritage

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