American Heritage Dictionary
(14)
Century Dictionary
(18)
GNU Webster's 1913
(3)
WordNet
(11)
Elsewhere on the web
But the trouble was the astonishing quickness with which this germ destroyed human beings, and the fact that it inevitably killed any human body it entered.— The Scarlet Plague
They looked scared, and hurried forward out of breath, walking and trotting in turn in order to hasten their progress, and moving their arms up and down so vigorously that they seemed to do more work with them than with their legs Renardet said to the doctor You know what the trouble is about Yes, a child found dead in the wood by Mederic That's quite correct.— The works of Guy de Maupassant, Vol. 5 (of 8) Une Vie and Other Stories
In its essence the trouble is a failure of power in the nervous centres upon which health of the bowels depends.— Papers on Health
They rushed by him and in at the gate, asking him what the trouble was there, but not waiting for an answer.— The Tragedy of Pudd'nhead Wilson
But the trouble was amply worth the taking; for I found the despatches, locked in an iron box and sealed with the great seal of the Governor of Cartagena, together with several other important-looking documents which subsequently proved to be of the utmost value.— The Log of a Privateersman

American Heritage Dictionary (1)
Century Dictionary (2)
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