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Definitions

Century Dictionary and Cyclopedia

  1. n. The act of exacerbating, or the state of being exacerbated; increase of violence or virulence; aggravation; exasperation.
  2. n. In medicine, an increase of violence in a disease; specifically, the periodical aggravation of the febrile condition in remittent and continued fevers: as, nocturnal exacerbations.

Wiktionary

  1. n. An increase in the severity of something (such as a disease)

GNU Webster's 1913

  1. n. The act of rendering more violent or bitter; the state of being exacerbated or intensified in violence or malignity.
  2. n. A periodical increase of violence in a disease, as in remittent or continuous fever; an increased energy of diseased and painful action.

WordNet 3.0

  1. n. action that makes a problem or a disease (or its symptoms) worse
  2. n. violent and bitter exasperation

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‘exacerbation’ has been looked up 1166 times, added to 3 lists, and has a Scrabble score of 23.