mutation

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It involves two PCR reactions and then you run it through sequencing machines and it pulls out whether the mutation is there or not.

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Definitions (25)

Toggle American Heritage definitions American Heritage Dictionary (6)

  1. noun The act or process of being altered or changed.
  2. noun An alteration or change, as in nature, form, or quality.
  3. noun Genetics A change of the DNA sequence within a gene or chromosome of an organism resulting in the creation of a new character or trait not found in the parental type.

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Toggle GNU Webster definitions GNU Webster's 1913 (1)

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Examples (50)

  • What I'm searching for is a durable mutation -- that's what all of us are searching for. —  Scott McCloud on comics
  • Our poetry is our mutation, our life. —  Philippe Starck thinks deep on design
  • The preponderance of Asians leads Stapledon to propose that the starting point for the mutation was somewhere in Central Asia, perhaps Mongolia, which is reasonable enough, but I don't see any genetic trail that could have led from the Asian steppes to France, Sweden, or England. —  Asimov'sSF,April-May2008
  • This mutation was absent in 350 unaffected French control subjects. —  New England Journal of Medicine
  • This mutation is in progress at the very moment when, to use Toynbee's expression, "an external proletariat" is forming on the southern and western shores of the Mediterranean Sea. —  The Brussels Journal - The Voice of Conservatism in Europe
 

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Roget's II Roget's II: The New Thesaurus

Allen's Allen's Synonyms and Antonyms

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mutation:   mutations
Roget's II: The New Thesaurus, Third Edition by the Editors of the American Heritage® Dictionary. Copyright © 2003, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Etymologies (2)

Toggle American Heritage etymologies American Heritage Dictionary (1)

  1. Middle English mutacioun, from Old French mutacion, from Latin mūtātiō, mūtātiōn-, from past participle of mūtāre, to change; see mutate.

Toggle Century etymologies Century Dictionary (1)

  1. from Middle English mutacioun, from Old French mutacion, mutation, French mutation = Spanish mutacion = Portuguese mutação = Italian mutazione, from Latin mutatio (n-), a changing, from mutare, past participle mutatus, change: see mute.
 

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/mjuˈteɪʃən/
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